Currently in Nuclear medicine training, I joined the LN2T in octobre 2022 to start my PhD research. The subject of my thesis aim to use the multimodality approach in the brain to study the links between neuronal activity, neurovascular & neurometabolic coupling. This project attends to characterize physiological mechanism at r esting state and with cognitive task, and seek disturbance in pathological situation like dementia or brain tumor. To achieve this we will be using EEG, fMRI and F-PET, a new functional investigation of the brain metabolism.